Tick-borne Encephalitis Virus
نویسندگان
چکیده
T encephalitis (TBE), which is caused by tickborne encephalitis virus (TBEV), is a potentially fatal disease of the central nervous system, mainly in humans, but also in monkeys, dogs (1), and horses. Ruminants such as goats, sheep, and cattle are considered to be sporadically infected subclinically. However, they might be the source of disease in humans who consume nonpasteurized milk and milk products (2). TBEV-associated central nervous system disease in ruminants is rare (3). TBEV occurs in natural foci and is endemic to many countries in Europe and parts of central and eastern Asia (4). The principal vectors for transmission are ticks of the genus Ixodes. Although TBEV in humans has been studied extensively, there are only a limited number of reports on TBEV in animals (5), especially horses. Only 2 reports were found in the German literature on the epidemiology of TBEV infection in horses (6,7), and 1 case report was found on clinical symptoms of TBE in a mare (8). The purpose of this study was to determine the status of TBEV infection in a large population of a single horse breed in Austria.
منابع مشابه
Genetic characterization of tick-borne flaviviruses: new insights into evolution, pathogenetic determinants and taxonomy.
Here, we analyze the complete coding sequences of all recognized tick-borne flavivirus species, including Gadgets Gully, Royal Farm and Karshi virus, seabird-associated flaviviruses, Kadam virus and previously uncharacterized isolates of Kyasanur Forest disease virus and Omsk hemorrhagic fever virus. Significant taxonomic improvements are proposed, e.g. the identification of three major groups ...
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SiRNA Inhibits Replication of Langat Virus, a Member of the Tick-Borne Encephalitis Virus Complex in Organotypic Rat Brain Slices
Tick-borne encephalitis virus is the causative agent of tick-borne encephalitis, a potentially fatal neurological infection. Tick-borne encephalitis virus belongs to the family of flaviviruses and is transmitted by infected ticks. Despite the availability of vaccines, approximately 2000-3000 cases of tick-borne encephalitis occur annually in Europe for which no curative therapy is available. Th...
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Rodents might maintain tick-borne encephalitis virus (TBEV) in nature through latent persistent infections. During 2 subsequent winters, 2008 and 2009, in Finland, we detected RNA of European and Siberian subtypes of TBEV in Microtus agrestis and Myodes glareolus voles, respectively. Persistence in rodent reservoirs may contribute to virus overwintering.
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